Lizzy Caplan

Actor

Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu’s Fleishman Is in Trouble (2022) have earned her nominations at the Primetime Emmy Awards.

Her first acting role was on the television series Freaks and Geeks (1999–2000). Since then, she had series-regular roles in several television series including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025).

Caplan’s film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend’s Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Cobweb (2023).

Description above from the Wikipedia article Lizzy Caplan, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Known For

Now You See Me 2 Not in library

Now You See Me 2

2016

The Simpsons Not in library

The Simpsons

1989

Mean Girls Not in library

Mean Girls

2004

127 Hours Not in library

127 Hours

2010

Cloverfield Not in library

Cloverfield

2008

The Interview Not in library

The Interview

2014

Family Guy Not in library

Family Guy

1999

Allied Not in library

Allied

2016

Smallville Not in library

Smallville

2001

The Disaster Artist Not in library

The Disaster Artist

2017

Acting

2026 Drag
2025 Now You See Me: Now You Don't as Lula
2025 Zero Day as Alexandra Mullen (6 episodes)
2023 Cobweb as Carol
2023 Fatal Attraction as Alex Forrest (8 episodes)
2022 The People We Hate at the Wedding as Marissa
2022 Fleishman Is in Trouble as Libby Epstein (8 episodes)
2021 Inside Job as Reagan Ridley (voice) (18 episodes)
2019 7 Up & Me as Self
2019 The Toll Road as Emily
2019 Truth Be Told as Lanie Buhrman / Josie Buhrman (8 episodes)
2018 Extinction as Alice In Library
2018 Castle Rock as Annie Wilkes (10 episodes)
2018 Das Boot as Carla Monroe (8 episodes)
2017 The Disaster Artist as Lizzy Caplan
2017 Ill Behaviour as Nadia (3 episodes)
2016 Now You See Me 2 as Lula
2016 Allied as Bridget Vatan
2016 Chelsea as Self (1 episode)
2016 Angie Tribeca as Deirdre (1 episode)
2015 The Night Before as Diana
2015 Close Up with The Hollywood Reporter as Self (1 episode)
2014 Beef as Audrey
2014 The Interview as Agent Lacey
2014 Late Night with Seth Meyers as Self - Guest (1 episode)
2014 Off Camera with Sam Jones as Self (1 episode)
2014 The Tonight Show Starring Jimmy Fallon as Self (1 episode)
2013 The Sidekick as Bailey
2013 Masters of Sex as Virginia Johnson (46 episodes)
2013 The Last Leg as Self (1 episode)
2012 Save the Date as Sarah
2012 Bachelorette as Gena Myers
2012 3, 2, 1... Frankie Go Boom as Lassie
2012 High Road as Sheila
2012 Queens of Country as Jolene Gillis
2012 Marvel One-Shot: Item 47 as Claire Wise
2012 Comedy Bang! Bang! as Self (1 episode)
2011 Home for Actresses as Lizzy
2011 New Girl as Julia Cleary (4 episodes)
2011 Mr. Sunshine as Vivian Cornelli (1 episode)
2010 Hot Tub Time Machine as April
2010 127 Hours as Sonja Ralston
2010 Successful Alcoholics as Lindsay
2010 The Last Rites of Ransom Pride as Juliette Flowers
2010 Conan as Self (2 episodes)
2009 Crossing Over as Marla
2009 The Cleveland Show
2009 Party Down as Casey Klein (21 episodes)
2009 Watch What Happens Live with Andy Cohen as Self - Guest (2 episodes)
2009 The League as Rebecca Ruxin (3 episodes)
2008 My Best Friend's Girl as Ami
2008 Cloverfield as Marlena
2008 True Blood as Amy (6 episodes)
2008 Childrens Hospital as Casey Klein (1 episode)
2008 Childrens Hospital as Harmony (1 episode)
2007 Crashing as Jacqueline
2006 Love Is the Drug as Sara Weller
2006 The Class as Kat Warbler (19 episodes)
2005 American Dad! as Debbie (voice) (5 episodes)
2005 Related as Marjee Sorelli (19 episodes)
2004 Mean Girls as Janis Ian
2003 Hardcore Action News as Lizzy Lyons
2003 Tru Calling as Avery Bishop (4 episodes)
2003 The Pitts as Faith Pitt (7 episodes)
2003 Jimmy Kimmel Live! as Self (1 episode)
2003 Jimmy Kimmel Live! as Self - Guest (3 episodes)
2002 Everybody's Doing It as Angela
2002 Orange County as Party Girl
2001 Undeclared as Beautiful Girl (1 episode)
2001 Smallville as Tina Greer (2 episodes)
2000 From Where I Sit as Lily
1999 Family Guy as Woman Arguing With Quagmire (voice) (1 episode)
1999 Once and Again
1999 Freaks and Geeks as Sara (4 episodes)
1997 The View as Self (1 episode)
1989 The Simpsons as Virginia Johnson (voice) (1 episode)

Production

2010 Successful Alcoholics Producer